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Systane® ULTRA Lubricant Eye Drops


For FAST-ACTING Relief for Dry Eye due to environmental conditions1,2


Don’t let Dry Eye symptoms caused by environmental factors such as screen time, air quality and/or seasonal issues (i.e. low humidity, high winds, dust) slow you down3,4. With Systane® ULTRA Lubricant Eye Drops, you’ll get fast-acting relief when you need it most1,2

Systane® Ultra Lubricant Eye Drops vial carton and product box

Key Benefits


  • FAST-ACTING Dry Eye Relief1,2 for irritated, dry eyes
  • For Dry Eye due to environmental conditions (such as screen time, air quality and/or seasonal issues
  • Easy to use Multi-dose Drop-Tainer™ bottle
  • For moderate, occasional sufferers*
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Product Information & Usage


Product Information

  • For Aqueous (Water) Deficient Dry Eye

  • Restores the mucin layer5

  • 2X more lubricating6 (compared to HA alone formulation)

  • Instantly hydrates the ocular (eye) surface

  • Available sizes: 10mL Drop-Tainer™ bottle. Also available in a 30ct unit dose vial

Product Usage

  • May be used as needed throughout the day

  • Place 1 or 2 drops in the affected eye(s) as needed and blink

  • Can be used with contact lenses**

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Systane® ULTRA FAQs


    Systane® ULTRA is a preserved formulation suitable for occasional users, which contains a very small quantity of the preservative (POLYQUAD™ 0.001%). Systane® ULTRA PRESERVATIVE-FREE lubricant eye drop is a preservative-free formulation, suitable for frequent users and available in a 30ct unit dose vial

    Yes, Systane® ULTRA lubricant eye drops can be used while wearing contact lenses.

    Systane® ULTRA can be used for 6 months after opening as long as the product has not expired. Always check the label for the expiration date.

    Ingredients & Safety


      Contains: A sterile solution containing polyethylene glycol 400, propylene glycol, hydroxypropyl guar, sorbitol, aminomethylpropanol, boric acid, potassium chloride, sodium chloride, POLYQUAD™ (polyquaternium-1) 0.001% preservative, and purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.

      For ocular use only.

      If solution changes color or becomes cloudy, do not use.

      To avoid contamination, never touch the dropper tip of the container to any surface.

      Replace cap after using.

      Stop using and consult your eye care professional if you experience:

      • Persistent eye discomfort,

      • Vision changes,

      • Excessive tearing,

      • Redness of the eye,

      Keep out of reach of children. If swallowed, get medical help.

      *Based on internal assessment and patient segmentation
      **Please refer to relevant instructions for use


      1. Davitt WF, Bloomenstein M, Christensen M, Martin AE. Efficacy in patients with dry eye after treatment with a new lubricant eye drop formulation. J Ocul Pharmacol Ther. 2010;26(4):347-353.
      2. Christensen MT, Martin AE, Bloomenstein M. A comparison of efficacy between Systane Ultra and Optive lubricant eye drops when tested with dry eye patients. Optometry. 2009;80(6):315.
      3. MarketScope LLC. 2019 Dry Eye Products Market Report: A Global Analysis for 2018 to 2024. St. Louis, MO: MarketScope LLC; 2019.
      4. Craig JP, Nelson JD, Azar DT, et al. TFOS DEWS II Report Executive Summary. Ocular Surface. 15(2017):802-812.
      5. Aguilar A, Berra M et at. Efficacy of polyethylene glycol-propylene glycol-based lubricant eye drops in reducing squamous mataplasia in patients with dry eye disease. Clin Opthalmol. 2018;12;1237-1243.
      6. Rangarajan R, Kraybill B, Ogundele A, Ketelson H. Effects of hyaluronic acid/hydroxypropyl guar artificial tear solution on protection, recovery, and lubricity in models of corneal epithelium. J Ocul Pharmacol Ther. 2015;31(8):491-497.


      Consult your healthcare or eye care professional for use, precautions, warnings and contraindications.