General FAQs About Systane^® and Dry Eye

See our answers to your most frequently asked questions about Systane^® and dry eye symptoms below.

General FAQs About Systane^® and Dry Eye

See our answers to your most frequently asked questions about Systane^® and dry eye symptoms below.

Is it normal for Systane® COMPLETE PRESERVATIVE-FREE to be cloudy white in color?

Yes. Systane® COMPLETE PRESERVATIVE-FREE contains a nano-emulsion of mineral oil and phospholipids that give it a cloudy white appearance. Shake well before use.

What are the differences between Systane® COMPLETE, Systane® ULTRA and Systane® HYDRATION eye drops?

Systane® offers several different types of eye drops, each designed to provide different levels of dry eye relief. Here are the differences between our eye drop families:

Longest lasting, up to 8 hours of relief¹
Formulated for: All types of dry eye
Systane^® Complete provides our longest lasting relief—clinically proven for up to 8 hours¹ — and provides relief for all major types of dry eye¹, both aqueous (lack of tear production) and evaporative (often due to MGD, where tears evaporate too quickly due to an inadequate lipid or oil layer in the tear film.

Long-lasting relief
Formulated for: Aqueous dry eye (lack of tear production)
Systane^® Hydration is formulated for immediate, long-lasting relief². It contains hydroxypropyl guar (HP-Guar) and Hyaluronate to reduce friction and restore natural moisture balance. This product is similar to Systane® ULTRA, but longer lasting. It’s a good fit for those recovering from eye surgery like refractive or cataract surgery.^3,4

Temporary relief
Formulated for: Aqueous dry eye (lack of tear production)
Systane^® Ultra offers fast-acting^5,6 relief from dryness, irritation, and discomfort. This product is a good fit for aqueous dry eye (lack of tear production).

Ask your eye doctor or pharmacist to determine the best Systane® eye drops for your needs.

Can I use Systane® after cataract surgery?

Yes. Systane® HYDRATION PRESERVATIVE-FREE is a good choice for dry eye drops after cataract surgery.³

REFERENCES:

1. Silverstein S, Yeu E, Tauber J, et al. Symptom Relief Following a Single Dose of Propylene Glycol-Hydroxypropyl Guar Nanoemulsion in Patients with Dry Eye Disease: A Phase IV, Multicenter Trial. Clin Ophthalmol. 2020;14:3167-3177.

2. Rolando M, Autori S, Badino F, Barabino S. Protecting the ocular surface and improving the quality of life of dry eye patients: a study of the efficacy of an HP-guar containing ocular lubricant in a population of dry eye patients. J Ocul Pharmacol Ther. 2009;25(3):271-278.

3. Davidson R. Efficacy evaluation of Systane Ultra in patients with dry eye undergoing cataract surgery. Poster presented at 30th Congress of the European Society of Cataract and Refractive Surgeons, Milan, Italy; Sept 8-12, 2012.

4. Cañones-Zafra R, et al. Comparison of Two Topical Lubricants on the Corneal Surface Recovery and Patient Discomfort After Photorefractive Keratectomy. Ophthalmol Ther. 2024 Jan;13(1):397-407.

5. Davitt WF, Bloomenstein M, Christensen M, Martin AE. Efficacy in patients with dry eye after treatment with a new lubricant eye drop formulation. J Ocul Pharmacol Ther. 2010;26(4):347-353.

6. Christensen MT, Martin AE, Bloomenstein M. A comparison of efficacy between Systane Ultra and Optive lubricant eye drops when tested with dry eye patients. Optometry. 2009;80(6):315.

Consult your healthcare or eye care professional for use, precautions, warnings and contraindications.

General FAQs About Systane® and Dry Eye