SYSTANE® COMPLETE Preservative-Free Eye Drops
Fast hydration and tear evaporation protection
Our most advanced dry eye solution with 8 hours of symptom relief now in a preservative-free formula ideal for sensitive eyes.
*vs SYSTANE® BALANCE

*Silverstein S, Yeu E, Tauber J, et al. Symptom Relief Following a Single-Dose of Propylene Glycol-Hydroxypropy Guar Nanoemultion in Patients with Dry Eye Disease: A Phase IV, Multicenter Trial. Clin Ophthalmol. 2020;14:3167-3177.
**Assessment based on assumption of 1 bottle of SYSTANE® COMPLETE MDPF for 60 days of use, and two unit dose vials used per day.
† Compared to single-dose vials.
†† Compared to SYSTANE® HYDRATION PF single-dose vials.
SYSTANE® COMPLETE Preservative-Free FAQs
SYSTANE® COMPLETE PF provides 8 hours of clinically proven relief for all major types of dry eye. Its preservative-free formula is ideal for sensitive eyes.
SYSTANE® COMPLETE PF is preservative-free, ideal for sensitive eyes.
No.
Yes.
Nano-droplet technology features the rapid delivery of this soothing drop over the entire eye surface—resulting in better coverage vs SYSTANE® BALANCE. It provides fast hydration, evaporation protection and long-lasting relief.
SYSTANE® COMPLETE PF provides instant dry eye relief.
Use 1-2 drops per eye as needed.
Place 1-2 drops in affected eye(s) as needed and blink.
No. SYSTANE® COMPLETE PF is available in our new multidose bottle that is easier to use vs single-dose vials.
Contact lens wearers can use the product before inserting or after taking out their contact lenses.
Yes. However, we recommend using SYSTANE® HYDRATION PF with HydroBoost technology to restore moisture directly after cataract surgery.
No. It treats dry or irritated eyes.
The product is milky white. It contains mineral oil and phospholipids as inactive ingredients that give it its milky white appearance.
No, it has not been tested on dogs. It has been approved for human use only.
Drug Facts
Shake well before using. Put 1 or 2 drops in the affected eye(s) as needed.
USES
- for the temporary relief of burning and irritation due to dryness of the eye
- for the temporary relief of discomfort due to minor irritations of the eye or to exposure to wind or sun
- for use as a protectant against further irritation or to relieve dryness of the eye
- for use as a lubricant to prevent further irritation or to relieve dryness of the eye
Active Ingredients
Propylene Glycol 0.6%
Purpose
Lubricant
Inactive Ingredients
Boric acid, dimyristoyl phosphatidylglycerol, hydroxypropyl guar, mineral oil, polyoxl 40 stearate, sorbitan tristearate, sorbitol and purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH
For external use only.
Do not use if this product changes color or if you are sensitive to any ingredient in this product.
When using this product, do not touch tip of container to any surface to avoid contamination, and replace cap after each use.
Stop use and ask a doctor if you experience any of the following:
- eye pain
- changes in vision
- continued redness or irritation of the eye
- condition worsens or persists longer than 72 hours
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Store at room temperature.
Other Products You Might Like:

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Offers a thick gel formulation that provides a protective layer on the eye for lasting dry eye symptom relief and protection.
Still not sure? Take the dry eye quiz.
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