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SYSTANE® COMPLETE Preservative-Free Eye Drops


Fast hydration and tear evaporation protection


Our most advanced dry eye solution with 8 hours of symptom relief in a preservative-free formula ideal for sensitive eyes. 


Available in a 10mL multi-dose bottle and 30 count single-use vials.

SYSTANE® COMPLETE Lubricant Eye Drops

Woman putting drops of Systane Complete Preservative Free in her eye

Open Your Eyes To Lasting Relief


  • Effective Relief

    Our most advanced COMPLETE formula provides 8 hours of relief for all types of dry eye in just one drop. 

  • Preservative-Free

    Our advanced technology is available in a preservative-free solution, which is ideal for sensitive eyes. 

  • Contact Lens Friendly*

    Safe for use with Soft Contact Lenses.

    *Not a rewetting drop

SYSTANE® COMPLETE Preservative-Free FAQs

    Both the Systane Complete Preservative-Free multi-dose bottle and single-use vials contain the same preservative-free formula. The only difference is that the single-use vials are more convenient for keeping in multiple locations, but must be discarded after each use.

    SYSTANE® COMPLETE PF provides 8 hours of clinically proven relief for all major types of dry eye. Its preservative-free formula is ideal for sensitive eyes.

    SYSTANE® COMPLETE PF is preservative-free, ideal for sensitive eyes.



    Nano-droplet technology features the rapid delivery of this soothing drop over the entire eye surface—resulting in better coverage vs SYSTANE® BALANCE. It provides fast hydration, evaporation protection and long-lasting relief.

    SYSTANE® COMPLETE PF provides instant dry eye relief.

    Use 1-2 drops per eye as needed.

    Place 1-2 drops in affected eye(s) as needed.


    Yes. Systane Complete PF is safe for use with soft contact lenses, but it is not a rewetting drop.

    Yes. However, we recommend using SYSTANE® HYDRATION PF with HydroBoost technology to restore moisture directly after cataract surgery.

    No. It provides relief for burning or irritation due to dry eyes

    The product is milky white. It contains mineral oil and phospholipids as inactive ingredients that give it its milky white appearance.

    No, it has not been tested on dogs. It has been approved for human use only.

    Drug Facts

      Shake well before using. Put 1 or 2 drops in the affected eye(s) as needed.



      • for the temporary relief of burning and irritation due to dryness of the eye
      • for the temporary relief of discomfort due to minor irritations of the eye or to exposure to wind or sun
      • for use as a protectant against further irritation or to relieve dryness of the eye
      • for use as a lubricant to prevent further irritation or to relieve dryness of the eye

      Active Ingredients
      Propylene Glycol 0.6%



      Inactive Ingredients
      Boric acid, dimyristoyl phosphatidylglycerol, hydroxypropyl guar, mineral oil, polyoxl 40 stearate, sorbitan tristearate, sorbitol and purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH

      For external use only.


      Do not use if this product changes color or if you are sensitive to any ingredient in this product.


      When using this product, do not touch tip of container to any surface to avoid contamination, and replace cap after each use. 


      Stop use and ask a doctor if you experience any of the following:

      • eye pain
      • changes in vision 
      • continued redness or irritation of the eye
      • condition worsens or persists longer than 72 hours


      Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.


      Store at room temperature.

      Other Products You Might Like:

      SYSTANE® NIGHTTIME Eye Ointment

      SYSTANE® NIGHTTIME Eye Ointment


      Designed to keep your eyes lubricated and comfortable while you sleep.


      SYSTANE® Lubricant Eye Gel

      SYSTANE® Lubricant Eye Gel


      Offers a thick gel formulation that provides a protective layer on the eye for lasting dry eye symptom relief and protection.



      Still not sure? Take the dry eye quiz.


      Get personalized dry eye product recommendations and helpful tips to reduce symptoms and triggers that may impact your eyes. It’s time to find a plan that’s designed for you.




      Woman taking a dry eye quiz on her phone.